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A Phase 1, Randomized, Open-label Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult Participants

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Trial Profile

A Phase 1, Randomized, Open-label Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult Participants

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2024

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At a glance

  • Drugs MRNA-1574 (Primary)
  • Indications HIV infections
  • Focus Adverse reactions; Pharmacodynamics

Most Recent Events

  • 21 Jul 2023 Planned End Date changed from 13 Oct 2023 to 24 Jun 2027.
  • 21 Jul 2023 Planned primary completion date changed from 13 Jul 2023 to 6 Sep 2023.
  • 06 Feb 2023 Status changed from suspended to active, no longer recruiting.

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