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A Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx, an Antisense Inhibitor of Angiotensinogen Production Administered Subcutaneously for 12 Weeks to Hypertensive Patients With Uncontrolled Blood Pressure

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Trial Profile

A Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx, an Antisense Inhibitor of Angiotensinogen Production Administered Subcutaneously for 12 Weeks to Hypertensive Patients With Uncontrolled Blood Pressure

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 01 Mar 2023

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At a glance

  • Drugs IONIS AGT LRx (Primary)
  • Indications Hypertension
  • Focus Therapeutic Use
  • Acronyms ASTRAAS
  • Sponsors Ionis Pharmaceuticals
  • Most Recent Events

    • 18 Feb 2023 Status changed from active, no longer recruiting to completed.
    • 04 Aug 2022 Planned End Date changed from 1 Jan 2023 to 1 Sep 2023.
    • 04 Aug 2022 Planned primary completion date changed from 1 Oct 2022 to 1 Sep 2022.

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