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An Open-Label, International, Multicenter, Phase 1b Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX (Capecitabine and Oxaliplatin) or Irinotecan in Patients With Advanced Gastric Cancer

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An Open-Label, International, Multicenter, Phase 1b Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX (Capecitabine and Oxaliplatin) or Irinotecan in Patients With Advanced Gastric Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 12 Jul 2024

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At a glance

  • Drugs Capecitabine (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary) ; Venadaparib (Primary)
  • Indications Gastric cancer; Oesophageal cancer
  • Focus Adverse reactions
  • Sponsors Idience

    • Most Recent Events

    • 04 Jun 2024 Results(n=26) evaluating the association between the presence of HRD gene mutations and the efficacy of venadaparib , presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 20 Jan 2024 Results (n=26) evaluating the association of HRD and efficacy of irinotecan and venadaparib combined, in patients with metastatic GC who had failed at least 2 lines of therapy, presented at the 2024 Gastrointestinal Cancers Symposium
    • 07 Aug 2022 Planned End Date changed from 31 Dec 2023 to 31 Mar 2024.

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