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A Phase 2, Open-Label 20-Week Study to Evaluate the Safety and Efficacy of Setmelanotide in Subjects With Hypothalamic Obesity

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Trial Profile

A Phase 2, Open-Label 20-Week Study to Evaluate the Safety and Efficacy of Setmelanotide in Subjects With Hypothalamic Obesity

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Nov 2024

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At a glance

  • Drugs Setmelanotide (Primary)
  • Indications Obesity
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Rhythm
  • Most Recent Events

    • 18 Nov 2024 According to a Rhythm media release, A cross-sectional analysis of 50 patients aged 2 to 17 years, with rare MC4R pathway diseases who participated in one of five different clinical trials of setmelanotide, including this one, was presented at European Society for Paediatric Endocrinology (ESPE 2024), held Nov 16-18, 2024, at Liverpool, UK.
    • 05 Nov 2024 According to a Rhythm Health media release, data from the extension phase of the this trial will be presented During The Obesity Societys ObesityWeek conference in San Antonio in November 2024.
    • 29 Apr 2024 According to a Rhythm Health media release, results from this study were published in the peer-reviewed journal The Lancet Diabetes & Endocrinology.

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