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A Double-Blind, Randomized, Placebo-Controlled, Single and Multiple Dose Study Evaluating the Safety, Tolerability, and Pharmacokinetics of AB-836, an HBV Capsid Inhibitor, in Healthy Subjects and Subjects With Chronic HBV Infection

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Trial Profile

A Double-Blind, Randomized, Placebo-Controlled, Single and Multiple Dose Study Evaluating the Safety, Tolerability, and Pharmacokinetics of AB-836, an HBV Capsid Inhibitor, in Healthy Subjects and Subjects With Chronic HBV Infection

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 08 Aug 2023

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At a glance

  • Drugs AB-836 (Primary) ; Tenofovir disoproxil fumarate
  • Indications Hepatitis B
  • Focus Adverse reactions
  • Sponsors Arbutus Biopharma
  • Most Recent Events

    • 24 Jun 2023 Results (n=48) assessing the prevalence and impact of HBV core proteinvariants on virologic response to AB-836 treatment presented at the European Association for the Study of the Liver Congress 2023
    • 07 Jun 2023 According to an Arbutus Biopharma media release, data from this study will be presented at the European Association for the Study of the Liver (EASL) Congress 2023.
    • 01 Nov 2022 Status changed from recruiting to discontinued, according to an Arbutus Biopharma media release.
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