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A Phase 2, Multicenter, Randomized Study to Compare the Efficacy and Safety of MK-7684A or MK-7684A Plus Docetaxel Versus Docetaxel Monotherapy in the Treatment of Participants With Metastatic Non-small Cell Lung Cancer With Progressive Disease After Treatment With a Platinum Doublet Chemotherapy and Immunotherapy

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A Phase 2, Multicenter, Randomized Study to Compare the Efficacy and Safety of MK-7684A or MK-7684A Plus Docetaxel Versus Docetaxel Monotherapy in the Treatment of Participants With Metastatic Non-small Cell Lung Cancer With Progressive Disease After Treatment With a Platinum Doublet Chemotherapy and Immunotherapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 Nov 2024

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At a glance

  • Drugs Pembrolizumab+vibostolimab (Primary) ; Docetaxel
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms KEYVIBE-002
  • Sponsors Merck Sharp & Dohme Corp.

    • Most Recent Events

    • 08 Nov 2024 Status changed from active, no longer recruiting to completed.
    • 06 Sep 2024 Planned End Date changed from 13 Aug 2027 to 17 Oct 2024.
    • 07 Dec 2023 Primary endpoint has not been met. (Progression Free Survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by Blinded Independent Central Review (BICR) Assessment), according to a Merck media release.

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