Trial Profile

A Phase I/II Trial of PARP Inhibition, Radiation, and Immunotherapy in Patients With Extensive-Stage Small Cell Lung Cancer (ES-SCLC) - PRIO Trial

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 13 Jan 2026

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At a glance

Drugs Carboplatin (Primary) ; Durvalumab (Primary) ; Etoposide (Primary) ; Olaparib (Primary)
Indications Brain metastases; Small cell lung cancer
Focus Adverse reactions
Acronyms PRIO; PRIO Trial

Most Recent Events

31 Dec 2025 Planned End Date changed from 31 Dec 2025 to 31 Dec 2027.
18 Dec 2025 Planned primary completion date changed from 31 Dec 2025 to 31 Dec 2027.
17 Nov 2025 Status changed from recruiting to active, no longer recruiting.

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