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A Phase IIIb, Single Arm, Multicenter Study of Atezolizumab in Combination With Bevacizumab to Investigate Safety and Efficacy in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy

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Trial Profile

A Phase IIIb, Single Arm, Multicenter Study of Atezolizumab in Combination With Bevacizumab to Investigate Safety and Efficacy in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 16 May 2025

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At a glance

  • Drugs Atezolizumab (Primary) ; Bevacizumab (Primary)
  • Indications Liver cancer
  • Focus Adverse reactions; Registrational
  • Acronyms ATHECA
  • Sponsors Roche

Most Recent Events

  • 08 May 2025 Status changed from completed to discontinued. The study was completed as pre-specified in the protocol, but terminated only for participants who were in the study even after 24 months of follow-up as specified in the protocol.
  • 14 May 2024 Status changed from active, no longer recruiting to completed.
  • 24 Oct 2023 Results of interim analysis assessing efficacy and acceptable safety profile in the pivotal IMbrave150 presented at the 48th European Society for Medical Oncology Congress

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