Trial Profile

A Phase III, Randomized Study of Bevacizumab and Paclitaxel in Combination With Atezolizumab as a Treatment for Patients With Locally Advanced Unresectable or Metastatic Hormone Receptor-positive HER2 Negative Breast Cancer

Status: Completed

Phase of Trial: Phase III

Latest Information Update: 25 Apr 2026

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At a glance

Drugs Atezolizumab (Primary) ; Bevacizumab; Paclitaxel
Indications Advanced breast cancer; Cancer metastases; Early breast cancer; HER2 negative breast cancer; Liver metastases; Male breast cancer
Focus Therapeutic Use
Acronyms AMBITION

21 Apr 2026 Status changed from active, no longer recruiting to completed.
14 Nov 2023 Planned End Date changed from 30 Jun 2025 to 30 Sep 2025.
14 Nov 2023 Planned primary completion date changed from 30 Jun 2025 to 30 Sep 2025.

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