The effect of semaglutide in subjects with non-cirrhotic non-alcoholic steatohepatitis
Latest Information Update: 23 Nov 2025
At a glance
- Drugs Semaglutide (Primary)
- Indications Hepatic fibrosis; Non-alcoholic steatohepatitis
- Focus Adverse reactions; Registrational; Therapeutic Use
- Acronyms ESSENCE
- Sponsors Novo Nordisk
Most Recent Events
- 28 Oct 2025 According to a Novo Nordisk media release, secondary analysis from this study will be presented in an Oral presentation (0010) and Efficacy response in subgroups will be presented in a poster (4042) on 10 November at the 76th Annual American Association for the Study of Liver Diseases (AASLD) congress, The Liver Meeting 2025, from 7 to 11 November in Washington D.C., U.S.
- 07 May 2025 According to a Novo Nordisk media release, once-weekly semaglutide 2.4 mg in MASH was submitted for regulatory approval in both the EU and US, and granted priority review in the US.
- 06 May 2025 According to a Novo Nordisk media release, data form this trial will be presented at the ECO 2025.