The effect of semaglutide in subjects with non-cirrhotic non-alcoholic steatohepatitis
Latest Information Update: 06 Sep 2026
At a glance
- Drugs Semaglutide (Primary)
- Indications Hepatic fibrosis; Non-alcoholic steatohepatitis
- Focus Adverse reactions; Registrational; Therapeutic Use
- Acronyms ESSENCE
- Sponsors Novo Nordisk
Most Recent Events
- 19 May 2026 According to a Novo Nordisk media release, data from this study will be presented at the European Association for the Study of the Liver (EASL) Annual Congress 2026 on 27-30 May in Barcelona, Spain.
- 19 May 2026 Results presented in a Novo Nordisk Media Release.
- 15 Dec 2025 According to a Novo Nordisk media release, based on results from this trial the Health Canada has issued marketing authorization with conditions [Notice of Compliance with Conditions (NOC/c)] for Wegovy (semaglutide injection) for the treatment of non-cirrhotic metabolic dysfunction-associated steatohepatitis (MASH) in adults with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis).