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An Open-Label, Multinational, Multicenter, Phase 3b/4 Study of Trastuzumab Deruxtecan in Patients With or Without Baseline Brain Metastasis With Previously Treated Advanced/Metastatic HER2-Positive Breast Cancer (DESTINY-Breast12)

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Trial Profile

An Open-Label, Multinational, Multicenter, Phase 3b/4 Study of Trastuzumab Deruxtecan in Patients With or Without Baseline Brain Metastasis With Previously Treated Advanced/Metastatic HER2-Positive Breast Cancer (DESTINY-Breast12)

Status: Active, no longer recruiting
Phase of Trial: Phase III/IV

Latest Information Update: 03 Dec 2024

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At a glance

  • Drugs Trastuzumab-deruxtecan (Primary)
  • Indications Advanced breast cancer; Brain metastases; HER2 positive breast cancer; Male breast cancer
  • Focus Therapeutic Use
  • Acronyms DESTINY-B12; DESTINY-Breast12
  • Sponsors AstraZeneca
  • Most Recent Events

    • 02 Dec 2024 According to a Daiichi Sankyo Company media release, results from this study will be presented in a Spotlight Poster Session on Friday, December 13, 7:00- 8:30 pm at San Antonio Breast Cancer Symposium (#SABCS24).
    • 01 Dec 2024 Results published in the Nature Medicine
    • 13 Sep 2024 Results published in the Daiichi Sankyo Inc Media Release

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