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A Phase 2, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Treatment Effect of Pentosan Polysulfate Sodium Compared to Placebo on Synovial Fluid Biomarkers in Participants with Knee Osteoarthritis Pain

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A Phase 2, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Treatment Effect of Pentosan Polysulfate Sodium Compared to Placebo on Synovial Fluid Biomarkers in Participants with Knee Osteoarthritis Pain

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 11 Apr 2024

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At a glance

  • Drugs Pentosan polysulfate (Primary)
  • Indications Musculoskeletal pain; Osteoarthritis
  • Focus Biomarker; Pharmacodynamics; Therapeutic Use
  • Sponsors Paradigm Biopharma

    • Most Recent Events

    • 04 Apr 2024 Planned End Date changed from 6 Dec 2024 to 6 Jan 2025.
    • 04 Apr 2024 Status changed from recruiting to active, no longer recruiting.
    • 04 May 2022 According to a Paradigm Biopharma media release, study is currently screening and enrolling subjects in eight sites across Australia and 21 of the 56 selected sites in the U.S.Site activations in the U.S. will continue, and UK and EU sites are also being initiated throughout CY22.

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