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A Phase 1/2, Open-label, Multicenter Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of CC-90011 in Combination With Venetoclax and Azacitidine in R/R Acute Myeloid Leukemia (AML) and Treatment-naïve Subjects With AML Who Are Not Eligible for Intensive Induction Chemotherapy

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Trial Profile

A Phase 1/2, Open-label, Multicenter Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of CC-90011 in Combination With Venetoclax and Azacitidine in R/R Acute Myeloid Leukemia (AML) and Treatment-naïve Subjects With AML Who Are Not Eligible for Intensive Induction Chemotherapy

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 07 Mar 2023

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At a glance

  • Drugs Azacitidine (Primary) ; Azacitidine (Primary) ; Pulrodemstat (Primary) ; Venetoclax (Primary)
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions
  • Sponsors Celgene Corporation

    • Most Recent Events

    • 01 Mar 2023 Status has been changed to discontinued.
    • 26 Jan 2022 Planned End Date changed from 22 May 2026 to 22 Apr 2025.
    • 09 Nov 2021 Phase of the trial is changed from Phase 1 to Phase 1/2.

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