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Trial Profile

Enhanced Histone H3.3-K27M Neoantigen Vaccine Therapy Against Diffuse Intrinsic Pontine Glioma (ENACTING)- A Phase I Clinical Trial

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 31 Jul 2023

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At a glance

Drugs Histone H3.3-K27M Neoantigen Vaccine - TCRCure Biopharma (Primary)
Indications Diffuse intrinsic pontine glioma
Focus Adverse reactions; Therapeutic Use
Acronyms ENACTING

Most Recent Events

25 Jul 2023 Planned End Date changed from 1 Apr 2024 to 1 Dec 2024.
25 Jul 2023 Planned primary completion date changed from 31 Mar 2023 to 31 Mar 2024.
06 Jun 2023 Preliminary findings of a phase I trial studying a neoantigen peptide vaccine targeting H3.3-K27M presented at the 59th Annual Meeting of the American Society of Clinical Oncology

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