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A Phase I Clinical Study Evaluating the Safety, Tolerability, MTD or MAD, PK, PD, and Antitumor Activity of TJ210001(a Fully Human C5aR Monoclonal Antibody) in Subjects With Advanced Solid Tumors

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Trial Profile

A Phase I Clinical Study Evaluating the Safety, Tolerability, MTD or MAD, PK, PD, and Antitumor Activity of TJ210001(a Fully Human C5aR Monoclonal Antibody) in Subjects With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Nov 2025

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At a glance

  • Drugs Izastobart (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions
  • Sponsors NovaBridge Biosciences

Most Recent Events

  • 29 Oct 2025 According to NovaBridge Biosciences media release, I-MAB Biopharma has changed its name to NovaBridge Biosciences.
  • 13 Mar 2023 Planned End Date changed from 1 Jan 2023 to 31 Dec 2025.
  • 13 Mar 2023 Planned primary completion date changed from 1 Jan 2023 to 31 Dec 2024.

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