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A Phase 1b/2 Open-Label Study of the Efficacy and Safety of Etigilimab (MPH313) Administered in Combination With Nivolumab to Subjects With Locally Advanced or Metastatic Solid Tumors (ACTIVATE)

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Trial Profile

A Phase 1b/2 Open-Label Study of the Efficacy and Safety of Etigilimab (MPH313) Administered in Combination With Nivolumab to Subjects With Locally Advanced or Metastatic Solid Tumors (ACTIVATE)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 01 Nov 2024

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At a glance

  • Drugs Etigilimab (Primary) ; Nivolumab (Primary)
  • Indications Adenocarcinoma; Carcinoma; Cervical cancer; Endometrial cancer; Fallopian tube cancer; Gastric cancer; Germ cell and embryonal neoplasms; Germ cell cancer; Head and neck cancer; Liposarcoma; Oesophageal cancer; Ovarian cancer; Peritoneal cancer; Sarcoma; Solid tumours; Squamous cell cancer; Uveal melanoma
  • Focus Therapeutic Use
  • Acronyms ACTIVATE
  • Sponsors Mereo BioPharma
  • Most Recent Events

    • 21 Feb 2024 Status changed from active, no longer recruiting to completed.
    • 24 Oct 2023 Results (n=76) assessing presented at the 48th European Society for Medical Oncology Congress.
    • 21 Oct 2023 According to a Mereo BioPharma media release, data from this trial presented at the ESMO 2023 Congress

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