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A Phase 2, Randomized, Double-blind, Placebo-Controlled Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Two Dose Levels of Belcesiran in Patients With Alpha-1 Antitrypsin Deficiency-Associated Liver Disease

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Trial Profile

A Phase 2, Randomized, Double-blind, Placebo-Controlled Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Two Dose Levels of Belcesiran in Patients With Alpha-1 Antitrypsin Deficiency-Associated Liver Disease

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 19 Jul 2024

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At a glance

  • Drugs Belcesiran (Primary)
  • Indications Alpha 1-antitrypsin deficiency
  • Focus Adverse reactions; Pharmacodynamics; Therapeutic Use
  • Acronyms ESTRELLA
  • Sponsors Dicerna Pharmaceuticals

    • Most Recent Events

    • 12 Jul 2024 Status changed from active, no longer recruiting to discontinued, because the development project was discontinued.
    • 15 May 2024 This trial has been completed in France, according to European Clinical Trials Database record.
    • 10 Apr 2024 This trial has been Discontinued in Portugal (End date: 2023-12-08) according to European Clinical Trials Database record.

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