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A Phase I Trial for the Evaluation of the Two-way Pharmacokinetic-pharmacodynamic (PD) Interaction of Gender Affirming Exogenous Estrogen (With Testosterone Suppression) on TDF/FTC PrEP in Transgender Women (TGW)

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A Phase I Trial for the Evaluation of the Two-way Pharmacokinetic-pharmacodynamic (PD) Interaction of Gender Affirming Exogenous Estrogen (With Testosterone Suppression) on TDF/FTC PrEP in Transgender Women (TGW)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 12 Jan 2025

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At a glance

  • Drugs Emtricitabine/tenofovir disoproxil fumarate (Primary) ; Estradiol; Iohexol; Leuprorelin
  • Indications HIV infections
  • Focus Pharmacokinetics

    • Most Recent Events

    • 11 Jan 2024 Planned End Date changed from 30 Jun 2024 to 30 Jun 2025.
    • 11 Jan 2024 Planned primary completion date changed from 1 Mar 2024 to 1 Mar 2025.
    • 08 Mar 2021 Status changed from not yet recruiting to recruiting.

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