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A Phase III, Randomized, Double-Blind, Placebo-Controlled Study of Platinum Plus Pemetrexed Chemotherapy Plus Osimertinib Versus Platinum Plus Pemetrexed Chemotherapy Plus Placebo in Patients With EGFRm, Locally Advanced or Metastatic NSCLC Who Have Progressed Extracranially Following First-Line Osimertinib Therapy (COMPEL)

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A Phase III, Randomized, Double-Blind, Placebo-Controlled Study of Platinum Plus Pemetrexed Chemotherapy Plus Osimertinib Versus Platinum Plus Pemetrexed Chemotherapy Plus Placebo in Patients With EGFRm, Locally Advanced or Metastatic NSCLC Who Have Progressed Extracranially Following First-Line Osimertinib Therapy (COMPEL)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 18 Sep 2024

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At a glance

  • Drugs Osimertinib (Primary) ; Carboplatin; Cisplatin; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms COMPEL
  • Sponsors AstraZeneca

    • Most Recent Events

    • 21 Feb 2024 Status changed from recruiting to active, no longer recruiting.
    • 29 Nov 2023 Planned number of patients changed from 204 to 80.
    • 29 Nov 2023 Planned primary completion date changed from 12 Jun 2024 to 30 Dec 2024.

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