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A Randomized Phase 3 Trial of Nivolumab (NSC# 748726) in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

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Trial Profile

A Randomized Phase 3 Trial of Nivolumab (NSC# 748726) in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 12 Jan 2025

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At a glance

  • Drugs Nivolumab (Primary) ; Cyclophosphamide; Doxorubicin; Etoposide; Filgrastim; Hyaluronidase; Pegfilgrastim; Prednisolone; Rituximab; Rituximab; Vincristine
  • Indications Diffuse large B cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Most Recent Events

    • 29 May 2024 Planned End Date changed from 31 Dec 2028 to 30 Sep 2027.
    • 29 May 2024 Planned primary completion date changed from 31 Dec 2028 to 30 Sep 2027.
    • 26 Sep 2023 Time frame changed from up to 5 years to up to 7 years.

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