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A Phase 2 Study of the Hepcidin Mimetic PTG-300 in Patients With Polycythemia Vera and Elevated Hematocrit (PACIFIC)

Trial Profile

A Phase 2 Study of the Hepcidin Mimetic PTG-300 in Patients With Polycythemia Vera and Elevated Hematocrit (PACIFIC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Mar 2024

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At a glance

  • Drugs Rusfertide (Primary)
  • Indications Polycythaemia vera
  • Focus Therapeutic Use
  • Acronyms PACIFIC
  • Sponsors Protagonist Therapeutics
  • Most Recent Events

    • 03 Mar 2024 Status changed from active, no longer recruiting to completed.
    • 12 Dec 2023 Results (n=20) assessing efficacy and safety of rusfertide in Asian patients with poor hematocrit, presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 15 Jun 2023 Results assessing relationship between rusfertide plasma concentrations and efficacy in patients with PV, presented at the 28th Congress of the European Haematology Association
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