A Phase III, Open-Label, Randomized Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
Latest Information Update: 01 Sep 2026
At a glance
- Drugs Atezolizumab (Primary) ; Lenvatinib; Sorafenib
- Indications Liver cancer
- Focus Registrational; Therapeutic Use
- Acronyms IMbrave251
- Sponsors Roche
Most Recent Events
- 25 Aug 2026 Planned End Date changed from 30 Jun 2026 to 14 Oct 2026.
- 25 Aug 2026 Planned primary completion date changed from 30 Jun 2026 to 14 Oct 2026.
- 17 Feb 2026 Planned primary completion date changed from 31 Mar 2026 to 30 Jun 2026.