A Phase III, Open-Label, Randomized Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
Latest Information Update: 25 Sep 2025
At a glance
- Drugs Atezolizumab (Primary) ; Lenvatinib; Sorafenib
- Indications Liver cancer
- Focus Registrational; Therapeutic Use
- Acronyms IMbrave251
- Sponsors Roche
Most Recent Events
- 07 Aug 2025 Planned primary completion date changed from 31 Jul 2025 to 26 Sep 2025.
- 18 May 2025 Planned primary completion date changed from 9 Jul 2025 to 31 Jul 2025.
- 17 Feb 2025 Planned End Date changed from 9 Jul 2025 to 17 Oct 2025.