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A Phase III, Open-Label, Randomized Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

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Trial Profile

A Phase III, Open-Label, Randomized Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 27 May 2025

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At a glance

  • Drugs Atezolizumab (Primary) ; Lenvatinib; Sorafenib
  • Indications Liver cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms IMbrave251
  • Sponsors Roche

Most Recent Events

  • 18 May 2025 Planned primary completion date changed from 9 Jul 2025 to 31 Jul 2025.
  • 17 Feb 2025 Planned End Date changed from 9 Jul 2025 to 17 Oct 2025.
  • 15 Oct 2024 Status changed from recruiting to active, no longer recruiting.

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