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A Phase 1 Open Label, Multi-Center Study to Evaluate the Safety and Tolerability of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) and Diffuse Midline Glioma (DMG)

Trial Profile

A Phase 1 Open Label, Multi-Center Study to Evaluate the Safety and Tolerability of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) and Diffuse Midline Glioma (DMG)

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 02 Jun 2025

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At a glance

  • Drugs Saposin C (Primary)
  • Indications Diffuse intrinsic pontine glioma
  • Focus Adverse reactions; Pharmacokinetics
  • Acronyms KONQUER
  • Sponsors Bexion Pharmaceuticals

Most Recent Events

  • 28 May 2025 According to a Bexion Pharmaceuticals media release, data from this study will be presented at the upcoming 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place May 30, 2025 - June 3, 2025, in Chicago, Illinois.
  • 20 Dec 2024 Status changed from active, no longer recruiting to discontinued due to companies decision to terminate study due to slow enrollment and the competitive landscape of the indication.
  • 28 Aug 2024 Planned End Date changed from 1 Dec 2024 to 1 Dec 2025.

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