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A Randomized and Placebo-Controlled Phase II Trial Targeting Dominant-Negative Missense Mutant P53 by Atorvastatin for Reducing the Risk of Longstanding Ulcerative Colitis-Associated Cancer

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Trial Profile

A Randomized and Placebo-Controlled Phase II Trial Targeting Dominant-Negative Missense Mutant P53 by Atorvastatin for Reducing the Risk of Longstanding Ulcerative Colitis-Associated Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Oct 2025

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At a glance

  • Drugs Atorvastatin (Primary)
  • Indications Colorectal cancer
  • Focus Biomarker; Pharmacodynamics

Most Recent Events

  • 05 Sep 2025 Planned End Date changed from 30 Jun 2026 to 30 Nov 2026.
  • 05 Sep 2025 Planned primary completion date changed from 31 Dec 2025 to 30 Jan 2026.
  • 29 Apr 2025 Planned End Date changed from 30 Mar 2026 to 30 Jun 2026.

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