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A Phase 3 Randomized Study of Lenvatinib in Combination With Pembrolizumab Versus Standard of Care in Participants With Metastatic Colorectal Cancer Who Have Received and Progressed On or After or Became Intolerant to Prior Treatment

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A Phase 3 Randomized Study of Lenvatinib in Combination With Pembrolizumab Versus Standard of Care in Participants With Metastatic Colorectal Cancer Who Have Received and Progressed On or After or Became Intolerant to Prior Treatment

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 30 Aug 2024

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At a glance

  • Drugs Lenvatinib (Primary) ; Pembrolizumab (Primary) ; Regorafenib; Tipiracil/trifluridine
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Merck Sharp & Dohme; Merck Sharp & Dohme Corp.

    • Most Recent Events

    • 13 May 2024 Planned End Date changed from 6 Sep 2024 to 27 Sep 2024.
    • 10 Nov 2023 Planned End Date changed from 11 Jan 2024 to 6 Sep 2024.
    • 07 Apr 2023 According to a Merck and Co media release, full evaluation of the data from this study, including pre-planned key subgroup analyses, is ongoing. The companies will work with investigators to share the results with the scientific community

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