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A Placebo-controlled, Participant, Investigator and Sponsor Blinded, Randomized Study to Evaluate the Pharmacokinetics and Pharmacodynamics of Inclisiran Treatment Given as Single Subcutaneous Injection in Chinese Participants With Elevated Low-density Lipoprotein Cholesterol (LDL-C) Despite Treatment With LDL-C Lowering Therapies (ORION-14)

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Trial Profile

A Placebo-controlled, Participant, Investigator and Sponsor Blinded, Randomized Study to Evaluate the Pharmacokinetics and Pharmacodynamics of Inclisiran Treatment Given as Single Subcutaneous Injection in Chinese Participants With Elevated Low-density Lipoprotein Cholesterol (LDL-C) Despite Treatment With LDL-C Lowering Therapies (ORION-14)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Dec 2021

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At a glance

  • Drugs Inclisiran (Primary)
  • Indications Hyperlipidaemia
  • Focus Pharmacodynamics; Pharmacokinetics
  • Acronyms ORION-14
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 02 Dec 2021 Status changed from active, no longer recruiting to completed.
  • 06 Oct 2021 Status changed from recruiting to active, no longer recruiting.
  • 18 May 2021 Planned End Date changed from 27 Sep 2021 to 9 Dec 2021.

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