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Pre-Transplant Immunosuppression and Related Haploidentical Hematopoietic Cell Transplantation for Patients With Severe Hemoglobinopathies

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Trial Profile

Pre-Transplant Immunosuppression and Related Haploidentical Hematopoietic Cell Transplantation for Patients With Severe Hemoglobinopathies

Status: Withdrawn prior to enrolment
Phase of Trial: Phase 0

Latest Information Update: 28 Feb 2023

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At a glance

  • Drugs Antithymocyte globulin (Primary) ; Bortezomib (Primary) ; Busulfan (Primary) ; Cyclophosphamide (Primary) ; Dexamethasone (Primary) ; Fludarabine (Primary) ; Mycophenolate mofetil (Primary) ; Mycophenolate mofetil (Primary) ; Rituximab (Primary) ; Tacrolimus (Primary) ; Tacrolimus (Primary)
  • Indications Beta-thalassaemia; Graft-versus-host disease; Haemoglobinopathies; Sickle cell anaemia
  • Focus Therapeutic Use

    • Most Recent Events

    • 16 Feb 2023 Planned End Date changed from 31 Oct 2023 to 5 Dec 2022.
    • 16 Feb 2023 Status changed from recruiting to withdrawn prior to enrolment. Withdrawn (Competing protocol opened in Adult SCT that will include pediatric patients and is now multi-center. No patients enrolled on study.)
    • 05 Mar 2021 New trial record

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