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An Open-label, Multicenter Phase 1 Dose Escalation Study to Characterize Safety, Tolerability, Preliminary Antitumor Activity, Pharmacokinetics, and Maximum Tolerated Dose of VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome

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Trial Profile

An Open-label, Multicenter Phase 1 Dose Escalation Study to Characterize Safety, Tolerability, Preliminary Antitumor Activity, Pharmacokinetics, and Maximum Tolerated Dose of VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 23 Nov 2023

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At a glance

  • Drugs Enitociclib (Primary)
  • Indications Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Richter's syndrome
  • Focus Adverse reactions
  • Sponsors Vincerx Pharma

    • Most Recent Events

    • 14 Nov 2023 Status changed from recruiting to discontinued.
    • 11 May 2023 According to Vincerx media release, the company anticipate dosing first patient in Phase 1b study of enitociclib in combination with an approved BTK inhibitor in patients with a high-risk chronic lymphocytic leukemia (CLL) in second quarter 2023.
    • 28 Mar 2023 According to Vincerx media release, dosing first patient in 1b study is expected in Q2 of 2023.
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