Trial Profile

A Phase III, Multicenter, Randomized, Open-label Trial to Evaluate the Safety and Efficacy of Systemic Therapy With Regorafenib and Pembrolizumab Versus Locoregional Therapy With Transarterial Chemoembolization or Transarterial Radioembolization, for the First-line Treatment of Intermediate-stage Hepatocellular Carcinoma With Beyond Up-to-7 Criteria

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 17 Sep 2025

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At a glance

13 May 2025 Planned End Date changed from 1 Apr 2027 to 28 Feb 2026.
13 May 2025 Planned primary completion date changed from 1 Oct 2025 to 28 Feb 2026.
17 Feb 2025 Status changed from recruiting to active, no longer recruiting.

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