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A Phase 1, First-in-human, Dose Escalation and Expansion, Multicenter Study of XMT-1660 in Participants With Solid Tumors

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Trial Profile

A Phase 1, First-in-human, Dose Escalation and Expansion, Multicenter Study of XMT-1660 in Participants With Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 22 Mar 2024

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At a glance

  • Drugs XMT-1660 (Primary)
  • Indications Advanced breast cancer; Endometrial cancer; HER2 negative breast cancer; Male breast cancer; Ovarian cancer; Solid tumours
  • Focus Adverse reactions; First in man; Proof of concept; Therapeutic Use
  • Sponsors Mersana Therapeutics

    • Most Recent Events

    • 28 Feb 2024 According to Mersana media release, company ,Enrollment is expected to initiate tumor-specific expansion cohorts in the second quarter of 2024 and announce initial clinical data in mid-2024.
    • 21 Feb 2024 Planned number of patients changed from 166 to 319.
    • 21 Feb 2024 Planned End Date changed from 1 Jan 2026 to 1 May 2027.

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