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A Phase 3, Randomized, Double-Blind Trial of Two Formulations of Setmelanotide (Daily and Weekly) With a Crossover to Open-Label Once Weekly Setmelanotide in Patients With Specific Gene Defects in the Melanocortin-4 Receptor Pathway Who Are Currently on a Stable Dose of the Once Daily Formulation

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A Phase 3, Randomized, Double-Blind Trial of Two Formulations of Setmelanotide (Daily and Weekly) With a Crossover to Open-Label Once Weekly Setmelanotide in Patients With Specific Gene Defects in the Melanocortin-4 Receptor Pathway Who Are Currently on a Stable Dose of the Once Daily Formulation

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 29 Nov 2024

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At a glance

  • Drugs Setmelanotide (Primary)
  • Indications Bardet-Biedl Syndrome; Obesity
  • Focus Pharmacokinetics; Registrational
  • Acronyms SWITCH Study
  • Sponsors Rhythm

    • Most Recent Events

    • 30 Nov 2023 Status changed from recruiting to completed.
    • 07 Nov 2023 According to a Rhythm Pharmaceuticals media release, pharmacokinetic and tolerability data from this study is expected in the fourth quarter of 2023.
    • 05 Nov 2023 This trial has been completed in Netherlands, according to European Clinical Trials Database record.

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