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A Randomized, Double-blind Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral NX-13 in Active Ulcerative Colitis

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Trial Profile

A Randomized, Double-blind Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral NX-13 in Active Ulcerative Colitis

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Mar 2025

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At a glance

  • Drugs Amelenodor (Primary)
  • Indications Ulcerative colitis
  • Focus Adverse reactions
  • Sponsors Landos Biopharma

Most Recent Events

  • 21 Mar 2024 According to a Landos Biopharma media release, R & D expenses were $3.1 million for the fourth quarter of 2023, compared to $3.4 million for the fourth quarter of 2022. The decrease was primarily attributable to reduced clinical activities due to the wind down of the omilancor and LABP-104 programs and a reduction in NX-13 Phase 1b clinical trial expenses, partially offset by the initiation of the NX-13 Phase 2 trial.
  • 21 Mar 2024 According to a Landos Biopharma media release, in November 2023, a peer-reviewed manuscript describing the safety, tolerability, pharmacokinetic and clinical efficacy results for the NX-13 Phase 1b trial in patients with UC was published in the Journal of Crohns and Colitis.
  • 21 Mar 2024 According to a Landos Biopharma media release, additional findings from the Phase 1b study of NX-13 for the treatment of UC, including detailed results on the rapid symptomatic relief and improvement in multiple biomarkers observed in the study presented at the American College of Gastroenterology (ACG) 2023 Annual Scientific Meeting.

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