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Phase III Study of Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive, First-line Metastatic Breast Cancer (DESTINY-Breast09)

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Trial Profile

Phase III Study of Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive, First-line Metastatic Breast Cancer (DESTINY-Breast09)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 20 Jun 2024

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At a glance

  • Drugs Pertuzumab (Primary) ; Trastuzumab-deruxtecan (Primary) ; Docetaxel; Paclitaxel; Taxanes; Trastuzumab
  • Indications Advanced breast cancer; HER2 positive breast cancer; Male breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms DESTINY-Breast09
  • Sponsors AstraZeneca; AstraZeneca AB; Daiichi Sankyo Inc
  • Most Recent Events

    • 12 Jun 2024 Planned primary completion date changed from 28 Mar 2025 to 24 Jul 2025.
    • 14 Nov 2023 Status changed from recruiting to active, no longer recruiting.
    • 06 Jun 2023 Planned primary completion date changed from 30 Dec 2024 to 28 Mar 2025.
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