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A 3-Arm, Randomized, Blinded, Active-Controlled, Phase II Study of RO7121661, a PD1-TIM3 Bispecific Antibody and RO7247669, a PD1-LAG3 Bispecific Antibody, Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus

Trial Profile

A 3-Arm, Randomized, Blinded, Active-Controlled, Phase II Study of RO7121661, a PD1-TIM3 Bispecific Antibody and RO7247669, a PD1-LAG3 Bispecific Antibody, Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Mar 2025

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At a glance

  • Drugs Lomvastomig (Primary) ; Tobemstomig (Primary) ; Nivolumab
  • Indications Oesophageal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Sponsors Roche

Most Recent Events

  • 28 Feb 2025 Status changed from active, no longer recruiting to completed.
  • 29 Jun 2023 Status changed from recruiting to active, no longer recruiting.
  • 19 Jun 2023 This trial has been Completed in Czechia, According to European Clinical Trials Database record.

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