Trial Profile

A Pilot Study to Evaluate the Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 26 May 2026

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At a glance

Drugs Domvanalimab (Primary) ; Etrumadenant (Primary) ; Zimberelimab (Primary)
Indications Brain metastases; Meningeal carcinomatosis; Non-small cell lung cancer; Squamous cell cancer
Focus Therapeutic Use

06 May 2026 Planned End Date changed from 30 Apr 2026 to 31 Dec 2030.
06 May 2026 Planned primary completion date changed from 30 Apr 2026 to 31 Oct 2026.
05 Nov 2025 Planned End Date changed from 31 Dec 2029 to 30 Apr 2026.

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