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A Phase 2a, Double-blind, Placebo-Controlled, Multi-Center Study to Assess the Efficacy, Safety, and Tolerability of IRL201104 in Adult Participants With Active Eosinophilic Esophagitis (EoE)

Trial Profile

A Phase 2a, Double-blind, Placebo-Controlled, Multi-Center Study to Assess the Efficacy, Safety, and Tolerability of IRL201104 in Adult Participants With Active Eosinophilic Esophagitis (EoE)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 May 2025

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At a glance

  • Drugs IRL 201104 (Primary)
  • Indications Eosinophilic oesophagitis
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Revolo Biotherapeutics

Most Recent Events

  • 30 Jan 2024 According to a Revolo Biotherapeutics media release, Based on the results from RVLO 121-04, the company plans to initiate a Phase 2b trial of 1104 in 2024,which will evaluate higher dose levels of 1104 and a longer duration of therapy.
  • 30 Jan 2024 According to a Revolo Biotherapeutics media release, the company received Orphan Drug Designation from FDA to 1104 ,for eosinophilic esophagitis treatment.
  • 30 Jan 2024 According to a Revolo Biotherapeutics media release,Evan Dellon is a Principal Investigator for the Phase 2a clinical trial.

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