Phase 1 double-blind, placebo-controlled trial assessing the safety, tolerability and PK of islatravir administered using a drug-eluting implant placed subdermally in healthy participants
Latest Information Update: 05 Dec 2022
At a glance
- Drugs Islatravir (Primary)
- Indications HIV infections
- Focus Adverse reactions; Pharmacokinetics
- Acronyms IMPLANT
- Sponsors Merck Sharp & Dohme
- 29 Nov 2022 Results assessing the safety, tolerability and pharmacokinetics of islatravir Eluting Subdermal Implants for Pre-exposure Prophylaxis Against HIV-1 Infection published in the JAIDS
- 15 Mar 2021 New trial record
- 10 Mar 2021 Data from this study and from in vitro assessments of the ISL implants in establishing a threshold islatravir-TP concentration of 0.05 pmol/million cells in PBMCs, presented at the 28th Conference on Retroviruses and Opportunistic Infections.