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TiNivo-2: A Phase 3, Randomized, Controlled, Multicenter, Open-label Study to Compare Tivozanib in Combination With Nivolumab to Tivozanib Monotherapy in Subjects With Renal Cell Carcinoma Who Have Progressed Following One or Two Lines of Therapy Where One Line Has an Immune Checkpoint Inhibitor

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Trial Profile

TiNivo-2: A Phase 3, Randomized, Controlled, Multicenter, Open-label Study to Compare Tivozanib in Combination With Nivolumab to Tivozanib Monotherapy in Subjects With Renal Cell Carcinoma Who Have Progressed Following One or Two Lines of Therapy Where One Line Has an Immune Checkpoint Inhibitor

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 02 May 2024

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At a glance

  • Drugs Nivolumab (Primary) ; Tivozanib (Primary)
  • Indications Renal cell carcinoma
  • Focus Registrational; Therapeutic Use
  • Acronyms TiNivo-2
  • Sponsors AVEO Oncology
  • Most Recent Events

    • 27 Jun 2023 According to a AVEO Oncology media release, company expects to share initial results from the TiNivo-2 study when the data mature, which is anticipated in the second half of 2024.
    • 26 Jun 2023 Status changed from recruiting to active, no longer recruiting.
    • 04 Aug 2022 According to a AVEO Oncology media release, enrollment is expected to be completed in the second quarter of 2023.
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