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Safety and efficacy of humanized anti‐CD19 CAR‐T (hCAR‐T) therapy in patients with B‐cell malignancies with HBV infection

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Trial Profile

Safety and efficacy of humanized anti‐CD19 CAR‐T (hCAR‐T) therapy in patients with B‐cell malignancies with HBV infection

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 19 Mar 2021

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At a glance

  • Drugs Anti-CD19 chimeric antigen receptor T cells therapy-Shanghai Jibei biotechnology (Primary) ; Cyclophosphamide; Entecavir; Fludarabine; Tenofovir
  • Indications B-cell leukaemia; B-cell lymphoma; Diffuse large B cell lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 19 Mar 2021 New trial record
    • 01 Feb 2021 Results assessing safety and efficacy of utilizing humanized anti-CD19 chimeric antigen receptor-T cell therapy to treat relapsed refractory diffuse large B-cell lymphoma (DLBCL) and acute lymphoblastic leukemia (ALL) patients with HBV infection, published in the Hematological Oncology.

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