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A Phase 2, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg, 20 mg, and 40 mg Compared to Placebo for Relief of Episodic Heartburn in Subjects With Symptomatic Non-Erosive Gastroesophageal Reflux Disease

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Trial Profile

A Phase 2, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg, 20 mg, and 40 mg Compared to Placebo for Relief of Episodic Heartburn in Subjects With Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 28 Sep 2023

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At a glance

  • Drugs Vonoprazan (Primary)
  • Indications Heartburn
  • Focus Proof of concept; Therapeutic Use
  • Acronyms PHALCON-NERD on-demand
  • Sponsors Phathom Pharmaceuticals

    • Most Recent Events

    • 26 Sep 2023 Results comparing the efficacy and safety of on-demand vonoprazan versus placebo in patients with NERD, published in the Alimentary Pharmacology and Therapeutics
    • 08 Jan 2023 According to a Phathom Pharmaceuticals media release, results from this study were previously presented at the American College of Gastroenterology (ACG) 2022 Annual Scientific Meeting.
    • 23 Oct 2022 According to a Phathom Pharmaceuticals media release, Ronnie Fass, M.D., director of the Division of Gastroenterology and Hepatology and medical director of the Digestive Health Center at MetroHealth in Cleveland, Ohio, is a lead investigator of this trial.

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