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An Adaptive, Regimen Finding, Safety and Tolerability Study of TCD601 (Siplizumab), a Human Anti-CD2 Antibody, Combined With Donor Bone Marrow Cell Infusion and Non-myeloablative Conditioning, for Tolerance Induction in Living Donor Renal Transplantation

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An Adaptive, Regimen Finding, Safety and Tolerability Study of TCD601 (Siplizumab), a Human Anti-CD2 Antibody, Combined With Donor Bone Marrow Cell Infusion and Non-myeloablative Conditioning, for Tolerance Induction in Living Donor Renal Transplantation

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 22 Apr 2025

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At a glance

  • Drugs Siplizumab (Primary) ; Corticosteroid; Cyclophosphamide; Mycophenolate mofetil; Rituximab; Tacrolimus; Tocilizumab
  • Indications Renal transplant rejection
  • Focus Therapeutic Use
  • Acronyms PANORAMA
  • Sponsors ITBMed Biopharmaceuticals

    • Most Recent Events

    • 17 Apr 2025 Status changed from recruiting to active, no longer recruiting.
    • 28 Oct 2022 Planned End Date changed from 1 Aug 2027 to 1 Jan 2030.
    • 28 Oct 2022 Planned primary completion date changed from 1 Jul 2024 to 1 Jan 2027.

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