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A Phase II/III Randomized Study of R-MiniCHOP With or Without CC-486 (Oral Azacitidine) in Participants Age 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma, Grade IIIB Follicular Lymphoma, Transformed Lymphoma, and High-Grade B-Cell Lymphomas With MYC AND BCL2 and/or BCL6 Rearrangements

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A Phase II/III Randomized Study of R-MiniCHOP With or Without CC-486 (Oral Azacitidine) in Participants Age 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma, Grade IIIB Follicular Lymphoma, Transformed Lymphoma, and High-Grade B-Cell Lymphomas With MYC AND BCL2 and/or BCL6 Rearrangements

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 17 Oct 2024

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At a glance

  • Drugs Azacitidine (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Rituximab; Rituximab; Vincristine
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 16 Apr 2024 Planned End Date changed from 31 Mar 2025 to 1 Mar 2026.
    • 16 Apr 2024 Planned primary completion date changed from 31 Mar 2025 to 1 Mar 2026.
    • 04 Apr 2023 Status changed from suspended to recruiting.

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