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A Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ALPN-303 in Adult Healthy Volunteers

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ALPN-303 in Adult Healthy Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 26 Nov 2023

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At a glance

  • Drugs Povetacicept (Primary) ; Povetacicept (Primary)
  • Indications Sjogren's syndrome; Systemic lupus erythematosus
  • Focus Adverse reactions; First in man
  • Acronyms RUBY-1
  • Sponsors Alpine Immune Sciences
  • Most Recent Events

    • 15 Nov 2023 According to an Alpine Immune Sciences media release, data from this study were presented at the American College of Rheumatology Convergence 2023, November 10-15, 2023.
    • 03 Nov 2023 According to an Alpine Immune Sciences media release, the company presented safety, tolerability, pharmacokinetic, and pharmacodynamic data at the American Association of Neuromuscular & Electrodiagnostic Medicine Annual Meeting (AANEM), November 1-3, 2023 in Phoenix, Arizona.
    • 05 Sep 2023 According to Alpine Immune Sciences media release, safety, tolerability, pharmacokinetic, and pharmacodynamic data of this study will be presented at 148th Annual American Neurological Association (ANA) Meeting in Philadelphia, PA.

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