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A Phase 1, Open Label, Fixed Sequence Study to Evaluate the Effect of BLD-0409 on the Single Dose Pharmacokinetics of a Cocktail of Probe Substrates for CYP450 Enzymes in Healthy Volunteers

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Trial Profile

A Phase 1, Open Label, Fixed Sequence Study to Evaluate the Effect of BLD-0409 on the Single Dose Pharmacokinetics of a Cocktail of Probe Substrates for CYP450 Enzymes in Healthy Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Sep 2022

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At a glance

  • Drugs Cudetaxestat (Primary) ; Bupropion; Caffeine; Dextromethorphan; Fexofenadine; Flurbiprofen; Midazolam; Omeprazole
  • Indications Cholangitis; Idiopathic pulmonary fibrosis; Inflammatory bowel diseases; Kidney disorders; Liver disorders; Non-alcoholic steatohepatitis; Scleroderma
  • Focus Pharmacokinetics
  • Sponsors Blade Therapeutics

Most Recent Events

  • 04 Sep 2022 According to a Blade Therapeutics media release, results from multiple phase I trials [NCT04146805, NCT04814472, NCT04939467 and NCT04814498] presented at European Respiratory Society (ERS) International Congress 2022
  • 04 Sep 2022 Results from multiple phase I trials [NCT04146805, NCT04814472, NCT04939467 and NCT04814498] published in the Blade Therapeutics Media Release
  • 22 Aug 2022 According to a Blade Therapeutics media release, data from four completed phase 1 studies[NCT04146805, NCT04814472, NCT04939467 and NCT04814498] will be presented at the at the European Respiratory Society (ERS) International Congress 2022.

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