Trial Profile

LIBRETTO-432: A Placebo-controlled Double-Blinded Randomized Phase 3 Study of Adjuvant Selpercatinib Following Definitive Locoregional Treatment in Participants With Stage IB-IIIA RET Fusion-Positive NSCLC

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 09 Mar 2026

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At a glance

04 Mar 2026 Planned End Date changed from 1 Apr 2028 to 1 May 2028.
16 Feb 2026 Primary endpoint (Event-Free Survival (EFS)) has been met, according to the Results published in the Eli Lilly and Company Media Release.
16 Feb 2026 Results published in the Eli Lilly and Company Media Release.

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