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LIBRETTO-432: A Placebo-controlled Double-Blinded Randomized Phase 3 Study of Adjuvant Selpercatinib Following Definitive Locoregional Treatment in Participants With Stage IB-IIIA RET Fusion-Positive NSCLC

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Trial Profile

LIBRETTO-432: A Placebo-controlled Double-Blinded Randomized Phase 3 Study of Adjuvant Selpercatinib Following Definitive Locoregional Treatment in Participants With Stage IB-IIIA RET Fusion-Positive NSCLC

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 12 Jul 2024

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At a glance

  • Drugs Selpercatinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms LIBRETTO-432
  • Sponsors Eli Lilly and Company; Loxo Oncology
  • Most Recent Events

    • 04 Jun 2024 Results presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
    • 02 Feb 2024 Planned End Date changed from 30 Nov 2032 to 30 Aug 2032.
    • 02 Feb 2024 Planned primary completion date changed from 31 Aug 2028 to 31 May 2027.
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