Trial Profile

SPARK-ALL: A Multi-center, Open-label, Single-arm Phase 2/3 Trial Evaluating the Safety and Pharmacokinetics of Calaspargase Pegol for Treatment of Adults Aged 22 To >65 Years With Newly-diagnosed Philadelphia-negative ALL

Status: Active, no longer recruiting

Phase of Trial: Phase II/III

Latest Information Update: 15 Oct 2025

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At a glance

Drugs Calaspargase pegol (Primary)
Indications Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma; Precursor T-cell lymphoblastic leukaemia-lymphoma
Focus Adverse reactions; Therapeutic Use

28 Feb 2025 Planned End Date changed from 3 Feb 2027 to 9 Feb 2026.
28 Feb 2025 Planned primary completion date changed from 3 Feb 2027 to 9 Feb 2026.
28 Feb 2025 Status changed from recruiting to active, no longer recruiting.

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