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TALAPRO-3: A PHASE 3, RANDOMIZED, DOUBLE-BLIND, STUDY OF TALAZOPARIB WITH ENZALUTAMIDE VERSUS PLACEBO WITH ENZALUTAMIDE IN MEN WITH DDR GENE MUTATED METASTATIC CASTRATION-SENSITIVE PROSTATE CANCER

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Trial Profile

TALAPRO-3: A PHASE 3, RANDOMIZED, DOUBLE-BLIND, STUDY OF TALAZOPARIB WITH ENZALUTAMIDE VERSUS PLACEBO WITH ENZALUTAMIDE IN MEN WITH DDR GENE MUTATED METASTATIC CASTRATION-SENSITIVE PROSTATE CANCER

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 12 Jun 2025

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At a glance

  • Drugs Enzalutamide (Primary) ; Talazoparib (Primary)
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms TALAPRO-3
  • Sponsors Pfizer

Most Recent Events

  • 29 May 2025 Planned primary completion date changed from 17 Nov 2025 to 18 Sep 2025.
  • 13 May 2025 Planned primary completion date changed from 18 Sep 2025 to 17 Nov 2025.
  • 20 Nov 2023 Planned End Date changed from 10 Apr 2027 to 7 Aug 2027.

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