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Investigation of the Pharmacokinetics, Safety and Tolerability of Runcaciguat in Participants With Hepatic Impairment (Classified as Child Pugh A or B) and in a Control Group of Age-, Weight-, and Gender-matched Participants Following a Single Oral 15 mg Modified Release (MR) Tablet Dose in a Non-randomized, Non-controlled, Non-blinded, Observational Study With Group Stratification

Trial Profile

Investigation of the Pharmacokinetics, Safety and Tolerability of Runcaciguat in Participants With Hepatic Impairment (Classified as Child Pugh A or B) and in a Control Group of Age-, Weight-, and Gender-matched Participants Following a Single Oral 15 mg Modified Release (MR) Tablet Dose in a Non-randomized, Non-controlled, Non-blinded, Observational Study With Group Stratification

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Runcaciguat (Primary)
  • Indications Renal failure
  • Focus Pharmacokinetics
  • Sponsors Bayer

Most Recent Events

  • 13 Jul 2021 Status changed from recruiting to discontinued(This study is prematurely terminated due to changes in sponsor's overall development strategy. The decision of termination is not related to any safety concern of the compound.)
  • 20 May 2021 Planned End Date changed from 5 Jan 2022 to 15 Mar 2022.
  • 21 Apr 2021 Status changed from not yet recruiting to recruiting.

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